One-pot tandem cyclization of enantiopure asymmetric cis-2,5-disubstituted pyrrolidines: Facile access to chiral 10-heteroazatriquinanes

• Ping-An Wang,
• Sheng-Yong Zhang and
• Henri B. Kagan

Beilstein J. Org. Chem. 2013, 9, 265–269, doi:10.3762/bjoc.9.32

• configurations of these new chiral 10-heteroazatriquinanes are confirmed by X-ray single-crystal diffraction analysis. Keywords: cis-2,5-disubstituted pyrrolidine; 10-heteroazatriquinane; tandem cyclization; X-ray single-crystal diffraction analysis; Introduction The azatriquinane derivatives are an important